Largest artery Crossword Clue
Looking for the answer to “Largest artery” from the USA Today crossword of January 7, 2026? It has 5 letters. Flip the tiles one at a time, try a hint first, or look through the rest of that puzzle.
Crossword answer
USA TODAY, JANUARY 7, 2026
Tap a tile to see one letter, or show the whole answer.
AORTA is the answer to “Largest artery”. It means a main artery.
Hints
Three clues to the answer, gentle first. Open one at a time.
Hint 1 Meaning
A main artery.
Hint 2 Anagram
Its letters, scrambled: OARAT.
Hint 3 Another clue
It has also been clued as “Main artery”.
Seen before
This clue also appeared in the USA Today on December 6, 2025, June 21, 2025, February 21, 2025, November 9, 2024.
Fresh clues from recent puzzles
Questions
What is the answer to “Largest artery”?
AORTA, 5 letters: a main artery.
When was “Largest artery” last seen in a crossword?
In the USA Today crossword of January 7, 2026, and 4 more times before that.
How many letters does the answer have?
5 letters, starting with A.