guys needs no unscrambling at all — the four-letter word is already the strongest play its own letters allow, banking 8 points in Scrabble as it stands. In all, 3 valid words come out of this rack, grouped by length below and checked for Words With Friends as well as Scrabble.
guys is the highest-scoring word from guys, worth 8 points in Scrabble. The top 3 of 3 words are shown here, with the full list organized by length below.
Only one four-letter word uses the letters in guys — and it is guys itself. No unscrambling is needed: the word is already playable as written, worth 8 points in Scrabble.
Unscrambling guys produces exactly one three-letter word: guy. It is an everyday word and an easy play, worth 7 points in Scrabble.
Unscrambling guys produces exactly one two-letter word: us. It is an everyday word and an easy play, worth 2 points in Scrabble.
Swap a single tile in guys and you get a different four-letter rack with its own word list. None of these appear in the results above — they share 3 of the 4 letters, not all of them.
guys is in the NWL, the official Scrabble word list for North America, and in the Words With Friends dictionary, so it's playable exactly as it stands and needs no unscrambling.
The 1-point gap between the two totals comes from the tile values themselves: Scrabble and Words With Friends price the same letters differently.
Dictionaries record five senses for guys. Scrabble and Words With Friends score tiles and not meanings, so every sense below is worth the same 8 points on a Scrabble board:
guys is the only four-letter word the same letters produce. No arrangement of the same tiles scores higher in Scrabble, so playing guys unchanged also takes the maximum points these letters offer.
The highest-scoring play from these letters is guys, worth 8 points in Scrabble, and no other word from guys earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in guys produce 3 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 1 four-letter word, 1 three-letter word and 1 two-letter word.