en, in, and ne tie for the highest Scrabble score from nie at 2 points. The top 3 of 3 words are shown here, with the full list organized by length below.
There are 3 two-letter words that can be made by unscrambling the letters in nie. If a familiar word is all you need, start with in. For points, the strongest plays are en, in, and ne — each worth 2 points in Scrabble.
The full list follows, sorted A to Z; every score reflects tile constraints and skips board bonuses.
The highest-scoring plays from these letters are en, in, and ne, worth 2 points in Scrabble, and nothing else built from nie earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in nie produce 3 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 3 two-letter words.