foo and oof tie for the highest Scrabble score from oof at 6 points. The top 3 of 3 words are shown here, with the full list organized by length below.
There are 2 three-letter words hiding in oof: one comes from rearranging its letters, and oof itself is already a playable word with no unscrambling required. No common everyday answer stands out among these three-letter results, so let the score decide: the highest-scoring words are foo and oof, each worth 6 points in Scrabble.
Unscrambling oof produces exactly one two-letter word: of. It is an everyday word and an easy play, worth 5 points in Scrabble.
oof is in the NWL, the official Scrabble word list for North America, but not in the Words With Friends dictionary, so it plays in Scrabble only.
oof is one of two three-letter words the same letters produce. No arrangement of the same tiles scores higher in Scrabble, so playing oof unchanged also takes the maximum points these letters offer.
The highest-scoring plays from these letters are foo and oof, worth 6 points in Scrabble, and nothing else built from oof earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in oof produce 3 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 2 three-letter words and 1 two-letter word.