pyx needs no unscrambling at all — the three-letter word is already the strongest play its own letters allow, banking 15 points in Scrabble as it stands. In all, 1 valid word comes out of this rack, grouped by length below and checked for Words With Friends as well as Scrabble.
pyx is the highest-scoring word from pyx, worth 15 points in Scrabble. The top 1 of 1 word is shown here, with the full list organized by length below.
Only one three-letter word uses the letters in pyx — and it is pyx itself. No unscrambling is needed: the word is already playable as written, worth 15 points in Scrabble.
Swap a single tile in pyx and you get a different three-letter rack with its own word list. None of these appear in the results above — they share 2 of the 3 letters, not all of them.
pyx is in the NWL, the official Scrabble word list for North America, and in the Words With Friends dictionary, so it's playable exactly as it stands and needs no unscrambling.
Both totals match, because every tile in pyx carries the same value on a Scrabble board and on a Words With Friends board.
Dictionaries record two senses for pyx. Scrabble and Words With Friends score tiles and not meanings, so every sense below is worth the same 15 points on a Scrabble board:
pyx is the only three-letter word the same letters produce. No arrangement of the same tiles scores higher in Scrabble, so playing pyx unchanged also takes the maximum points these letters offer.
The highest-scoring play from these letters is pyx, worth 15 points in Scrabble, and no other word from pyx earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in pyx produce 1 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 1 three-letter word.