drek needs no unscrambling at all — the four-letter word is already the strongest play its own letters allow, banking 9 points in Scrabble as it stands. In all, 6 valid words come out of this rack, grouped by length below and checked for Words With Friends as well as Scrabble.
drek is the highest-scoring word from drek, worth 9 points in Scrabble. The top 6 of 6 words are shown here, with the full list organized by length below.
Only one four-letter word uses the letters in drek — and it is drek itself. No unscrambling is needed: the word is already playable as written, worth 9 points in Scrabble.
Unscrambling drek produces exactly one three-letter word: red. It is an everyday word and an easy play, worth 4 points in Scrabble.
There are 4 two-letter words that can be made by unscrambling the letters in drek. No common everyday answer stands out among these two-letter results, so let the score decide: the highest-scoring words are de and ed, each worth 3 points in Scrabble.
The full list follows, sorted A to Z; every score reflects tile constraints and skips board bonuses.
Swap a single tile in drek and you get a different four-letter rack with its own word list. None of these appear in the results above — they share 3 of the 4 letters, not all of them.
drek is in the NWL, the official Scrabble word list for North America, and in the Words With Friends dictionary, so it's playable exactly as it stands and needs no unscrambling.
Both totals match, because every tile in drek carries the same value on a Scrabble board and on a Words With Friends board.
drek is the only four-letter word the same letters produce. No arrangement of the same tiles scores higher in Scrabble, so playing drek unchanged also takes the maximum points these letters offer.
The highest-scoring play from these letters is drek, worth 9 points in Scrabble, and no other word from drek earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in drek produce 6 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 1 four-letter word, 1 three-letter word and 4 two-letter words.