toxin needs no unscrambling at all — the five-letter word is already the strongest play its own letters allow, banking 12 points in Scrabble as it stands. In all, 18 valid words come out of this rack, grouped by length below and checked for Words With Friends as well as Scrabble.
toxin is the highest-scoring word from toxin, worth 12 points in Scrabble. The top 10 of 18 words are shown here, with the full list organized by length below.
Only one five-letter word uses the letters in toxin — and it is toxin itself. No unscrambling is needed: the word is already playable as written, worth 12 points in Scrabble.
Unscrambling toxin produces exactly one four-letter word: into. It is an everyday word and an easy play, worth 4 points in Scrabble.
There are 9 two-letter words that can be made by unscrambling the letters in toxin. If a familiar word is all you need, start with in, it and no. For points, the strongest plays are ox and xi — each worth 9 points in Scrabble.
Swap a single tile in toxin and you get a different five-letter rack with its own word list. None of these appear in the results above — they share 4 of the 5 letters, not all of them.
toxin is in the NWL, the official Scrabble word list for North America, and in the Words With Friends dictionary, so it's playable exactly as it stands and needs no unscrambling.
The 1-point gap between the two totals comes from the tile values themselves: Scrabble and Words With Friends price the same letters differently.
Dictionaries record one sense for toxin. Scrabble and Words With Friends score tiles and not meanings, so every sense below is worth the same 12 points on a Scrabble board:
toxin is the only five-letter word the same letters produce. No arrangement of the same tiles scores higher in Scrabble, so playing toxin unchanged also takes the maximum points these letters offer.
The highest-scoring play from these letters is toxin, worth 12 points in Scrabble, and no other word from toxin earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in toxin produce 18 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 1 five-letter word, 1 four-letter word, 7 three-letter words and 9 two-letter words.