no and on tie for the highest Scrabble score from on at 2 points. The top 2 of 2 words are shown here, with the full list organized by length below.
There are 2 two-letter words hiding in on: one comes from rearranging its letters, and on itself is already a playable word with no unscrambling required. Here the everyday answers and the top-scoring plays are one and the same: no and on, worth 2 points apiece in Scrabble.
on is in the NWL, the official Scrabble word list for North America, and in the Words With Friends dictionary, so it's playable exactly as it stands and needs no unscrambling.
The 1-point gap between the two totals comes from the tile values themselves: Scrabble and Words With Friends price the same letters differently.
Dictionaries record three senses for on. Scrabble and Words With Friends score tiles and not meanings, so every sense below is worth the same 2 points on a Scrabble board:
on is one of two two-letter words the same letters produce. No arrangement of the same tiles scores higher in Scrabble, so playing on unchanged also takes the maximum points these letters offer.
The highest-scoring plays from these letters are no and on, worth 2 points in Scrabble, and nothing else built from on earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in on produce 2 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 2 two-letter words.