dex and xed tie for the highest Scrabble score from xed at 11 points. The top 5 of 5 words are shown here, with the full list organized by length below.
There are 2 three-letter words hiding in xed: one comes from rearranging its letters, and xed itself is already a playable word with no unscrambling required. No common everyday answer stands out among these three-letter results, so let the score decide: the highest-scoring words are dex and xed, each worth 11 points in Scrabble.
Swap a single tile in xed and you get a different three-letter rack with its own word list. None of these appear in the results above — they share 2 of the 3 letters, not all of them.
xed is in the NWL, the official Scrabble word list for North America, but not in the Words With Friends dictionary, so it plays in Scrabble only.
xed is one of two three-letter words the same letters produce. No arrangement of the same tiles scores higher in Scrabble, so playing xed unchanged also takes the maximum points these letters offer.
The highest-scoring plays from these letters are dex and xed, worth 11 points in Scrabble, and nothing else built from xed earns more points in Scrabble. Words With Friends prices the same letters differently, so the top of the list changes on a Words With Friends board. Both scores count tile values only and exclude premium squares.
The letters in xed produce 5 valid words in the Scrabble and Words With Friends dictionaries. The word count by length is: 2 three-letter words and 3 two-letter words.